Description

Buy Alodorm Nitrazepam Australia

Buy Alodorm Nitrazepam Australia , sold under the brand name Mogadon among others,^[2][3] is a hypnotic drug of the benzodiazepine class used for short-term relief from severe, disabling anxiety and insomnia.^[4] It also has sedative (calming) properties,^[5] as well as amnestic (inducing forgetfulness), anticonvulsant, and skeletal muscle relaxant effects.

It was first synthesized in the late 1950s by a team of researchers at Hoffmann-La Roche in Switzerland.^[6] It was patented in 1961 and came into medical use in 1965.^[7]

Nitrazepam is used to treat short-term sleeping problems (insomnia),^[8] namely difficulty falling asleep, frequent awakening, early awakening, or a combination of each.

Nitrazepam is sometimes tried to treat epilepsy when other medications fail. It has been found to be more effective than clonazepam in the treatment of West syndrome, which is an age-dependent epilepsy, affecting the very young. In uncontrolled studies, nitrazepam has shown effectiveness in infantile spasms and is sometimes considered when other anti-seizure drugs have failed.^[9] However, drowsiness, hypotonia, and most significantly tolerance to anti-seizure effects typically develop with long-term treatment, generally limiting Nitrazepam to acute seizure management. Nitrazepam can also mitigate effects of alcohol withdrawal.^[10]

A light-activated derivative of nitrazepam (fulgazepam) has been developed for research purposes.^[11]

More common side effects may include: central nervous system depression, including somnolence, dizziness, depressed mood, fatigue, ataxia, headache, vertigo, impairment of memory, impairment of motor functions, a “hungover” feeling in the morning, slurred speech, decreased physical performance,^{[clarification needed]} numbed emotions, reduced alertness, muscle weakness, double vision, and inattention have been reported. Unpleasant dreams and rebound insomnia have also been reported.

Nitrazepam is a long-acting benzodiazepine with an elimination half-life of 15–38 hours (mean elimination half-life 26 hours).^[12] Residual “hangover” effects after nighttime administration of nitrazepam such as sleepiness, impaired psychomotor and cognitive functions may persist into the next day, which may impair the ability of users to drive safely and increases the risk of falls and hip fractures.^[13]

Less common side effects may include: Hypotension,^[14] faintness, palpitation, rash or pruritus, gastrointestinal disturbances, and changes in libido are less common. Very infrequently, paradoxical reactions may occur, for example, excitement, stimulation, hallucinations, hyperactivity, and insomnia. Also, depressed or increased dreaming, disorientation, severe sedation, retrograde amnesia, headache, hypothermia, and delirium tremens are reported.^[15] Severe liver toxicity has also been reported.^[16]